Annotation Overview for fig|159087.4.peg.1611 in Dechloromonas aromatica RCB:
Hydroxyacylglutathione hydrolase (EC 3.1.2.6)

current assignment	Hydroxyacylglutathione hydrolase (EC 3.1.2.6)	EC Number	3.1.2.6
taxonomy id	159087	contig	159087.4:NC_007298 (4,501,105bp)
internal links	genome browser | feature evidence | sequence	ACH Annotation Clearinghouse (ACH) The Annotation Clearinghouse offers a mapping of genes which are identical in sequence except for the start region (due to differences in start calling). [?]	show essentially identical genes
annotation history		run tool	Psi-BlastTMpredTMHMMGram negative PSORTGram negative SignalPGram positive PSORTGram positive SignalPLipoPInterProScanRadarPPSearchGram negative CELLOGram positive CELLOProDomPDB
FigFam	FIG000013
data base cross references (dbxref)	NCBI: 71907227 CMR: NTL02DA1595 RefSeq: YP_284814.1 NCBI: 71846848 UniProt: Q47FN7_DECAR UniProt: Q47FN7

Annotation History (history of similar genes)

Date	Annotator	Annotation
10/28/2004	rodionov	Set FIG function to Cytochrome cd1 Nitrite reductase [EC:1.7.2.1]
10/28/2004	rodionov	Set FIG function to Cytochrome cd1 nitrite reductase (EC:1.7.2.1)
11/5/2004	rodionov	Set FIG function to nitrite reductase (EC:1.7.2.1) homolog
11/30/2004	RossO	Set FIG function to Hydroxyacylglutathione hydrolase (EC 3.1.2.6)
7/19/2005	OlgaZ	Set FIG function to Hydroxyacylglutathione hydrolase (EC 3.1.2.6)

We have assigned the function "Hydroxyacylglutathione hydrolase (EC 3.1.2.6)" to the encoded protein. The protein occurs in 4 subsystems: "Cobalt-zinc-cadmium resistance", "Glutathione-regulated potassium-efflux system and associated functions", "Glutathione: Non-redox reactions", and "Methylglyoxal Metabolism". In "Cobalt-zinc-cadmium resistance", it appears to play a functional role that we have not associated with any other gene. In "Glutathione-regulated potassium-efflux system and associated functions", it appears to play a functional role that we have not associated with any other gene. In "Glutathione: Non-redox reactions", it appears to play a functional role that we have not associated with any other gene, and it occurs in close proximity on the chromosome with another gene from the same subsystem. In "Methylglyoxal Metabolism", it appears to play a functional role that we have not associated with any other gene. The function of genes having the same functional roles have been described in Saccharomyces cerevisiae (9261170), Salmonella typhimurium (17764159), Homo sapiens (15616553, 8550579) and Arabidopsis thaliana (9065762, 9349270). These are homologous proteins which implement the same function.

The chromosomal region of the focus gene (top) is compared with four similar organisms. The graphic is centered on the focus gene, which is red and numbered 1. Sets of genes with similar sequence are grouped with the same number and color. Genes whose relative position is conserved in at least four other species are functionally coupled and share gray background boxes. The size of the region and the number of genomes may be reset. Click on any arrow in the display to refocus the comparison on that gene. The focus gene always points to the right, even if it is located on the minus strand.